SCI期刊投稿 | 专刊 "Electrochemical Aptasensors in Clinical Diagnosis"

Special Issue "Electrochemical Aptasensors in Clinical Diagnosis"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Chemical Biology".

Deadline for manuscript submissions:30 June 2023

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Special Issue Editors

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Special Issue Information

Dear Colleagues,

The early detection of cancer and other diseases can only be achieved through the quantification of specific biomarkers (proteins, RNA, DNA, cells, etc.) at very low concentrations in biological fluids, the so-called liquid biopsy. This challenge requires new tools with improved selectivity and selectivity. Aptamers, synthetic single-stranded DNA or RNA molecules, meet the requirements of recognition elements and can be selected through an in vitro process called SELEX to bind to biomarker proteins or even certain regions within them. This provides an exciting opportunity to obtain receptors for specific features that make it possible to increase the sensitivity/specificity of the diagnostics. Similar to antibodies but more easily generated, with low production cost, low batch-to-batch variability, reversible folding properties, and low immunogenicity, aptamers are the ideal molecules to be engineered into biosensors (aptasensors), actuators and other devices. Aptasensors offer great potential to detect target proteins, and this field is progressing rapidly towards innovative and promising analytical devices. Electrochemical aptasensors are especially convenient due to their easy miniaturization and integration in microfluidic devices.

In this Special Issue, we seek manuscripts that cover the development of electrochemical aptasensors for their application in clinical diagnosis. The selection of novel aptamers and their characterization is also welcomed.

Dr. Ana Díaz-Fernández

Dr. Noemí de-los-Santos-Álvarez

Guest Editors

Manuscript Submission Information

Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on theInstructions for Authorspage.Moleculesis an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit theInstructions for Authorspage before submitting a manuscript. TheArticle Processing Charge (APC)for publication in thisopen accessjournal is 2300 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI'sEnglish editing serviceprior to publication or during author revisions.

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Keywords

aptamerselectrochemistryaptasensorsbiomarkersclinical diagnosiscancerSELEXbiosensors